Essec\Faculty\Model\Contribution {#2216
  #_index: "academ_contributions"
  #_id: "15979"
  #_source: array:26 [
    "id" => "15979"
    "slug" => "15979-clinical-burden-of-pneumococcal-disease-among-adults-in-france-a-retrospective-cohort-study"
    "yearMonth" => "2025-12"
    "year" => "2025"
    "title" => "Clinical burden of pneumococcal disease among adults in France: A retrospective cohort study"
    "description" => "BAILEY, M.D., FARGE, G., MOHANTY, S., BREAU-BRUNEL, M., ROY, G., DE POUVOURVILLE, G. ... JOHNSON, K.D. (2025). Clinical burden of pneumococcal disease among adults in France: A retrospective cohort study. <i>Human Vaccines & Immunotherapeutics</i>, 21(1), pp. 2515760."
    "authors" => array:13 [
      0 => array:3 [
        "name" => "DE POUVOURVILLE Gérard"
        "bid" => "B00072308"
        "slug" => "de-pouvourville-gerard"
      ]
      1 => array:1 [
        "name" => "Bailey M. Doyinsola"
      ]
      2 => array:1 [
        "name" => "Farge Gaëlle"
      ]
      3 => array:1 [
        "name" => "Mohanty Salini"
      ]
      4 => array:1 [
        "name" => "Breau-Brunel Manon"
      ]
      5 => array:1 [
        "name" => "Roy Gem"
      ]
      6 => array:1 [
        "name" => "de Wazieres Benoit"
      ]
      7 => array:1 [
        "name" => "Janssen Cécile"
      ]
      8 => array:1 [
        "name" => "Tauty Solenne"
      ]
      9 => array:1 [
        "name" => "Bugnard Françoise"
      ]
      10 => array:1 [
        "name" => "Goguillot Mélanie"
      ]
      11 => array:1 [
        "name" => "Bénard Stève"
      ]
      12 => array:1 [
        "name" => "Johnson Kelly D."
      ]
    ]
    "ouvrage" => ""
    "keywords" => array:8 [
      0 => "Invasive pneumococcal disease"
      1 => "clinical burden"
      2 => "fatality"
      3 => "incidence"
      4 => "mortality"
      5 => "non-bacteremic pneumococcal pneumonia"
      6 => "older adults"
      7 => "pneumococcal conjugate vaccine"
    ]
    "updatedAt" => "2025-09-18 10:59:43"
    "publicationUrl" => "https://doi.org/10.1080/21645515.2025.2515760"
    "publicationInfo" => array:3 [
      "pages" => "2515760"
      "volume" => "21"
      "number" => "1"
    ]
    "type" => array:2 [
      "fr" => "Articles"
      "en" => "Journal articles"
    ]
    "support_type" => array:2 [
      "fr" => "Revue scientifique"
      "en" => "Scientific journal"
    ]
    "countries" => array:2 [
      "fr" => null
      "en" => null
    ]
    "abstract" => array:2 [
      "fr" => "Pneumococcal disease (PD) is associated with high morbidity and mortality, specifically among individuals ≥65 years of age and those with underlying medical conditions (UMCs). This retrospective cohort study estimated the clinical burden of PD in adults ≥18 years of age with or without UMCs in France. Data were obtained from the French National Health Data System for four yearly cohorts (1 January 2015-31 December 2018). Characteristics of patients with UMCs, with or without PD (UMC population), and the incidence rate and lethality rate of PD leading to hospitalization (in-patient PD population), stratified by age and risk status, were described. In the UMC population (n = 7,947,622; mean age: 65 years), the incidence rate of in-patient PD episodes was 121.98 per 100,000 person-years and was highest among individuals ≥65 years of age (138.52) and in those considered medium-risk (102.45) or high-risk (165.77). In the in-patient PD population (n = 41,885), 59.6% were ≥65 years of age; 1-year all-cause mortality following the initial in-patient PD episode was 26.5%. Individuals ≥65 years of age (regardless of risk status) had a higher risk of PD leading to hospitalization than individuals 18-64 years of age. This study shows a high burden of PD in France due to in-patient PD among adults with UMCs, particularly in those ≥65 years of age, despite their eligibility for pneumococcal vaccination. This highlights the need for higher vaccination coverage, supported by the recent extension of vaccination to all people ≥65 years of age, regardless of their health risk status."
      "en" => "Pneumococcal disease (PD) is associated with high morbidity and mortality, specifically among individuals ≥65 years of age and those with underlying medical conditions (UMCs). This retrospective cohort study estimated the clinical burden of PD in adults ≥18 years of age with or without UMCs in France. Data were obtained from the French National Health Data System for four yearly cohorts (1 January 2015-31 December 2018). Characteristics of patients with UMCs, with or without PD (UMC population), and the incidence rate and lethality rate of PD leading to hospitalization (in-patient PD population), stratified by age and risk status, were described. In the UMC population (n = 7,947,622; mean age: 65 years), the incidence rate of in-patient PD episodes was 121.98 per 100,000 person-years and was highest among individuals ≥65 years of age (138.52) and in those considered medium-risk (102.45) or high-risk (165.77). In the in-patient PD population (n = 41,885), 59.6% were ≥65 years of age; 1-year all-cause mortality following the initial in-patient PD episode was 26.5%. Individuals ≥65 years of age (regardless of risk status) had a higher risk of PD leading to hospitalization than individuals 18-64 years of age. This study shows a high burden of PD in France due to in-patient PD among adults with UMCs, particularly in those ≥65 years of age, despite their eligibility for pneumococcal vaccination. This highlights the need for higher vaccination coverage, supported by the recent extension of vaccination to all people ≥65 years of age, regardless of their health risk status."
    ]
    "authors_fields" => array:2 [
      "fr" => "Management"
      "en" => "Management"
    ]
    "indexedAt" => "2025-12-06T07:21:43.000Z"
    "docTitle" => "Clinical burden of pneumococcal disease among adults in France: A retrospective cohort study"
    "docSurtitle" => "Journal articles"
    "authorNames" => "<a href="/cv/de-pouvourville-gerard">DE POUVOURVILLE Gérard</a>, Bailey M. Doyinsola, Farge Gaëlle, Mohanty Salini, Breau-Brunel Manon, Roy Gem, de Wazieres Benoit, Janssen Cécile, Tauty Solenne, Bugnard Françoise, Goguillot Mélanie, Bénard Stève, Johnson Kelly D."
    "docDescription" => "<span class="document-property-authors">DE POUVOURVILLE Gérard, Bailey M. Doyinsola, Farge Gaëlle, Mohanty Salini, Breau-Brunel Manon, Roy Gem, de Wazieres Benoit, Janssen Cécile, Tauty Solenne, Bugnard Françoise, Goguillot Mélanie, Bénard Stève, Johnson Kelly D.</span><br><span class="document-property-authors_fields">Management</span> | <span class="document-property-year">2025</span>"
    "keywordList" => "<a href="#">Invasive pneumococcal disease</a>, <a href="#">clinical burden</a>, <a href="#">fatality</a>, <a href="#">incidence</a>, <a href="#">mortality</a>, <a href="#">non-bacteremic pneumococcal pneumonia</a>, <a href="#">older adults</a>, <a href="#">pneumococcal conjugate vaccine</a>"
    "docPreview" => "<b>Clinical burden of pneumococcal disease among adults in France: A retrospective cohort study</b><br><span>2025-12 | Journal articles </span>"
    "docType" => "research"
    "publicationLink" => "<a href="https://doi.org/10.1080/21645515.2025.2515760" target="_blank">Clinical burden of pneumococcal disease among adults in France: A retrospective cohort study</a>"
  ]
  +lang: "en"
  +"_score": 8.714207
  +"_ignored": array:3 [
    0 => "abstract.en.keyword"
    1 => "abstract.fr.keyword"
    2 => "description.keyword"
  ]
  +"parent": null
}