Essec\Faculty\Model\Contribution {#2233
#_index: "academ_contributions"
#_id: "12651"
#_source: array:26 [
"id" => "12651"
"slug" => "current-challenges-for-assessing-the-long-term-clinical-benefit-of-cancer-immunotherapy-a-multi-stakeholder-perspective"
"yearMonth" => "2020-07"
"year" => "2020"
"title" => "Current challenges for assessing the long-term clinical benefit of cancer immunotherapy: a multi-stakeholder perspective"
"description" => "QUINN, C., GARRISON, L.P., POWNELL, A.K., ATKINS, M.B., PUYOU DE POUVOURVILLE, G., HARRINGTON, K. ... WU, E. (2020). Current challenges for assessing the long-term clinical benefit of cancer immunotherapy: a multi-stakeholder perspective. <i>Journal for ImmunoTherapy of Cancer</i>, 8(2), pp. e000648."
"authors" => array:11 [
0 => array:3 [
"name" => "PUYOU DE POUVOURVILLE Gérard"
"bid" => "B00072308"
"slug" => "de-pouvourville-gerard"
]
1 => array:1 [
"name" => "QUINN Casey"
]
2 => array:1 [
"name" => "GARRISON Louis P"
]
3 => array:1 [
"name" => "POWNELL Anja K"
]
4 => array:1 [
"name" => "ATKINS Michael B"
]
5 => array:1 [
"name" => "HARRINGTON Kevin"
]
6 => array:1 [
"name" => "ASCIERTO Paolo Antonio"
]
7 => array:1 [
"name" => "MCEWAN Phil"
]
8 => array:1 [
"name" => "WAGNER Samuel"
]
9 => array:1 [
"name" => "BORRILL John"
]
10 => array:1 [
"name" => "WU Elise"
]
]
"ouvrage" => ""
"keywords" => []
"updatedAt" => "2023-01-30 13:36:38"
"publicationUrl" => "http://dx.doi.org/10.1136/jitc-2020-000648"
"publicationInfo" => array:3 [
"pages" => "e000648"
"volume" => "8"
"number" => "2"
]
"type" => array:2 [
"fr" => "Articles"
"en" => "Journal articles"
]
"support_type" => array:2 [
"fr" => "Revue scientifique"
"en" => "Scientific journal"
]
"countries" => array:2 [
"fr" => null
"en" => null
]
"abstract" => array:2 [
"fr" => "Immuno-oncologics (IOs) differ from chemotherapies as they prime the patient’s immune system to attack the tumor, rather than directly destroying cancer cells. The IO mechanism of action leads to durable responses and prolonged survival in some patients. However, providing robust evidence of the long-term benefits of IOs at health technology assessment (HTA) submission presents several challenges for manufacturers. The aim of this article was to identify, analyze, categorize, and further explore the key challenges that regulators, HTA agencies, and payers commonly encounter when assessing the long-term benefits of IO therapies. Insights were obtained from an international, multi-stakeholder steering committee (SC) and expert panels comprising of payers, economists, and clinicians."
"en" => "Immuno-oncologics (IOs) differ from chemotherapies as they prime the patient’s immune system to attack the tumor, rather than directly destroying cancer cells. The IO mechanism of action leads to durable responses and prolonged survival in some patients. However, providing robust evidence of the long-term benefits of IOs at health technology assessment (HTA) submission presents several challenges for manufacturers. The aim of this article was to identify, analyze, categorize, and further explore the key challenges that regulators, HTA agencies, and payers commonly encounter when assessing the long-term benefits of IO therapies. Insights were obtained from an international, multi-stakeholder steering committee (SC) and expert panels comprising of payers, economists, and clinicians."
]
"authors_fields" => array:2 [
"fr" => "Management"
"en" => "Management"
]
"indexedAt" => "2024-11-22T05:21:52.000Z"
"docTitle" => "Current challenges for assessing the long-term clinical benefit of cancer immunotherapy: a multi-stakeholder perspective"
"docSurtitle" => "Articles"
"authorNames" => "<a href="/cv/de-pouvourville-gerard">PUYOU DE POUVOURVILLE Gérard</a>, QUINN Casey, GARRISON Louis P, POWNELL Anja K, ATKINS Michael B, HARRINGTON Kevin, ASCIERTO Paolo Antonio, MCEWAN Phil, WAGNER Samuel, BORRILL John, WU Elise"
"docDescription" => "<span class="document-property-authors">PUYOU DE POUVOURVILLE Gérard, QUINN Casey, GARRISON Louis P, POWNELL Anja K, ATKINS Michael B, HARRINGTON Kevin, ASCIERTO Paolo Antonio, MCEWAN Phil, WAGNER Samuel, BORRILL John, WU Elise</span><br><span class="document-property-authors_fields">Management</span> | <span class="document-property-year">2020</span>"
"keywordList" => ""
"docPreview" => "<b>Current challenges for assessing the long-term clinical benefit of cancer immunotherapy: a multi-stakeholder perspective</b><br><span>2020-07 | Articles </span>"
"docType" => "research"
"publicationLink" => "<a href="http://dx.doi.org/10.1136/jitc-2020-000648" target="_blank">Current challenges for assessing the long-term clinical benefit of cancer immunotherapy: a multi-stakeholder perspective</a>"
]
+lang: "fr"
+"_type": "_doc"
+"_score": 8.640402
+"parent": null
}