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Journal articles (2023), Therapies, 78 (1), pp. 81-94

Real-world data and evidence in health technology assessment: When are they complementary, substitutes, or the only sources of data compared to clinical trials?

PUYOU DE POUVOURVILLE Gérard , ARMOIRY Xavier, LAVOREL Aurélie, BILBAULT Pascal, MAUGENDRE Philippe, BENSIMON Lionel, BEZIZ Dan, BLIN Patrick, BORGET Isabelle, BOUÉE Stéphane, COLLIGNON Céline, DERVAUX Benoît, DURAND-ZALESKI Isabelle, JULIEN Marc, DE LÉONTAING Lucie, MAJEED Laureen, MARTELLI Nicolas, SÉJOURNÉ Thomas, VIPREY Marie

Within the life-cycle assessment of health technologies, real-world data (RWD) have until now been of secondary importance to clinical trial data. The availability of massive, better quality RWD, particularly with the emergence of connected devices, the improvement of methods for characterizing populations, make it possible to have a better insight into the effects of treatment, sometimes on a national scale the importance of RWD is likely to progress in the eyes of health technology assessors, going from being traditionally complementary to possibly replacing clinical trial data. Link to the article

PUYOU DE POUVOURVILLE, G., ARMOIRY, X., LAVOREL, A., BILBAULT, P., MAUGENDRE, P., BENSIMON, L. ... VIPREY, M. (2023). Real-world data and evidence in health technology assessment: When are they complementary, substitutes, or the only sources of data compared to clinical trials? Therapies, 78(1), pp. 81-94.

Keywords : #Real, #world-data, #Health-technology-assessment, #Decision-making